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Research Progress of Musculin in Regulating Immunocytes
LIU Yijia1,2, YU Jing1*, LIU Ke1,2, LI Suiyan2, GAO Wenda3, YAN Jun1*
(1State Key Laboratory of Trauma, Burns and Combined Injury, Department of Special War Wound, Institute of Surgery Research, Army Medical University, Chongqing 400042, China; 2School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China; 3Antagen Institute for Biomedical Research, Boston 02118, USA)
Abstract:
Musculin, a new transcription suppressor of basic helix-loop-helix structure, is not only involved in the generation, tissue development and differentiation of mammalian skeletal muscle, but also regulates the differentiation and function of T lymphocytes, B lymphocytes and innate lymphoid cells, indicating that this factor has a certain relationship with immune cells and may be used as a key regulatory factor for immune cells involved in immune diseases. Therefore, this paper summarized the recent research progress of Musculin in regulating immunocytes.
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